Side Effects. Nausea, vomiting, mild itching, or an unpleasant sensation in the mouth may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. The most common side effects of clotrimazole are redness, blistering, peeling, stinging, swelling, itching, hives, or burning at the site of application. Read about clotrimazole (Lotrimin [discontinued], Mycelex, Lotrimin-AF, Gyne-Lotrimin) medication prescribed for vaginal yeast infections, thrush, jock itch, athlete's foot, and tinea versicolor. Side effects, drug interaction, and dosage information is included. Consumer information about the medication CLOTRIMAZOLE LOZENGE - MUCOUS MEMBRANE (ORAL) (Mycelex), includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug CLOTRIMAZOLE LOZENGE - MUCOUS MEMBRANE (ORAL). Along with its needed effects, clotrimazole topical (the active ingredient contained in Mycelex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. MYCELEX® (clotrimazole) TROCHE. FOR TOPICAL ORAL ADMINISTRATION. DESCRIPTION. Each Mycelex® Troche contains 10 mg clotrimazole [1 -(o-chloro-a,a-diphenylbenzyl) imidazole], a synthetic antifungal agent, for topical use in the mouth. Some side effects of clotrimazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Side Effects. Burning, stinging, swelling, irritation, redness, pimple-like bumps, tenderness, or flaking of the treated skin may occur. If any of these effects persist or worsen, notify your. Drug Information on Mycelex Troche (clotrimazole) includes drug pictures, side effects, drug interactions, directions for use, symptoms of overdose, and what to avoid. SIDE EFFECTS. Abnormal liver function tests have been reported in patients treated with clotrimazole troches; elevated SGOT levels were reported in about 15% of patients in the clinical trials (See PRECAUTIONS section).